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  • Physicians who treat opioid addiction have the option of utilizing 'medication-assisted treatment', as well as the most common medications used in the treatment of opioid dependence today are methadone, naltrexone, and buprenorphine (Suboxone). Using two separate drugs to lose weight can be very effective you can find combinations in front of the FDA now awaiting approval. When dealing with weight loss and the people who go through it you ought to err along the side of caution and allow FDA do its job and demand some investigation be done so that the public recognizes the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies will be in business to generate income and that they would say everything to keep people on the medications. Researchers found that participants using this drug to get a year, dropped a few pounds within 4 weeks and have kept the weight off during the entire 56 weeks from the study. Contrave is often a combination with the drugs naltrexone and bupropion, which appears to reflect a whole new trend of weight-loss drugs which can be made up of more than one active ingredient, which might make them more potent and safer. Combo-pilling may be the newest fad or in addition to this the newest in the future under scrutiny and therefore it is just more publicly known although in the past, comb-pilling to lose weight has been around since the eighties. The biggest reason that by using a combination of pills has become popular could be the fact that by right now there aren't any long term prescription diet pills that have been approved by the FDA apart from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications even though some of the combinations are already rejected or have yet to be licensed by the FDA. Seizures can be a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug also can raise blood pressure and heartbeat, and really should not be used in those with a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise hypertension and heart rate and must not used in patients with uncontrolled high blood pressure levels, as well as by you are not heart-related and cerebrovascular (circulatory dysfunction impacting your brain) disease. Patients using a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients on the increased chance of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for smoking cessation. "There were no signs and symptoms of depression or suicidal thoughts in trial participants," said Fujioka.